ea0070oc1.3 | Adrenal and Cardiovascular Endocrinology | ECE2020
Cantini Giulia
, Armignacco Roberta
, de Assis Goncalves Diego
, Guasti Daniele
, Nesi Gabriella
, Romagnoli Paolo
, Mannelli Massimo
, Maggi Mario
, Luconi Michaela
The metabolic interplay occurring between the tumor microenvironment and cancer cells may represent a potential target for novel anti-cancer approaches. Among stromal components, adipocytes and adipose precursors have been shown to actively participate in tumor progression in several solid malignancies. In adrenocortical carcinoma (ACC), a rare endocrine neoplasia with a poor prognosis, cancer cells often infiltrate the fat mass surrounding the adrenal organ, enabling a possib...